Linked Life Data

580199

Source:http://linkedlifedata.com/resource/pubmed/id/580199

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1978-4-17
pubmed:abstractText
1. 1 h after i.p. injection of 150.6 mg/kg silybin-dihemisuccinate the synthesis of fatty acids and glycerolipids was studied. 2. Measured as 3H incorporation after i.v. injection of 3H2O the synthesis of fatty acids was enhanced by silybin. Incorporation of [1-14C]-acetic acid in fatty acids of the postmitochondrial supernatant of liver homogenates was not influenced by silybin. The enhanced synthesis of fatty acids seems to be caused by an enhanced concentration of citrate, which was paralleled by a lowered pyruvate concentration and pyruvate-dehydrogenase activity. 3. In liver homogenates of silybin-treated animals the acylation of [U-14C]-glycerol-3-phosphate was increased as a measure of glycerolipid synthesis.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0004-4172
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
51-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
[Increase in rat liver synthesis of fatty acids and glycerol phospholipids following parenteral application of silybin-dihemisuccinate].
pubmed:publicationType
Journal Article, English Abstract