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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1978-4-26
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pubmed:abstractText |
Morphological and behavioral responses to estradiol-17 beta (E2-17 beta) and estradiol-17 alpha (E2-17 alpha) were examined in a series of three experiments. The E2-17 beta augmented uterine growth in hamsters to a greater extent than did E2-17 alpha. Lordosis in ovariectomized adults was elicited by treatment with E2-17 beta but not with E2-17 alpha (each tested in combination with progesterone). When administered neonatally only E2-17 beta disrupted estrous cyclicity in the intact female and induced the ability to mount in ovariectomized, androgen-treated adults. These results suggest the existence of a stereospecific response to estrogenic stimulation in neural tissue comparable with that occurring in the uterus.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
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pubmed:issn |
0021-9940
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
7-12
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:564359-Animals,
pubmed-meshheading:564359-Animals, Newborn,
pubmed-meshheading:564359-Cricetinae,
pubmed-meshheading:564359-Dose-Response Relationship, Drug,
pubmed-meshheading:564359-Esters,
pubmed-meshheading:564359-Estradiol,
pubmed-meshheading:564359-Estrus,
pubmed-meshheading:564359-Female,
pubmed-meshheading:564359-Pregnancy,
pubmed-meshheading:564359-Sexual Behavior, Animal,
pubmed-meshheading:564359-Stereoisomerism,
pubmed-meshheading:564359-Uterus
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pubmed:year |
1978
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pubmed:articleTitle |
Differential influence of stereoisomers of estradiol on sexual behavior of female hamsters.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.
|