Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1978-1-27
pubmed:abstractText
Mycoplasma arthritidis, M. hominis, and M. arginini were tested for their ability to induce a cytotoxic response from normal CBA mouse lymphocytes against 51Cr-labeled allogeneic target cells. In most cases, the mycoplasmas alone were not toxic for the target cells. Furthermore, the mycoplasmas did not result in decreased lymphocyte viability but, in fact, contributed to enhanced lymphocyte survival. In the absence of normal CBA lymphocytes, mycoplasmas alone did not induce a significant amount of cell damage in either the allogeneic or the syngeneic target cells. Strains of M. arthritidis and M. hominis, when added to the lymphocyte-target cell mixtures, induced statistically significant increases in 51Cr release from both target cell types at each assay period after 6 h. The release of 51Cr was taken as a measure of cell death. M. arginini induced only low levels of cytotoxicity or none at all. Both arthritogenic and non-arthritogenic strains of M. arthritidis induced the cytotoxic response. The degree of cytotoxicity produced was directly related to the size of the initial inoculum. The presence or absence of serum in the culture medium did not contribute significantly to the cytotoxicity response.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-1083958, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-1130199, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-1193724, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-127011, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-1275576, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-13878126, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-14004931, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-16557773, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-4306341, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-4373395, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-4519141, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-4547395, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-4549025, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-4560750, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-4587519, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-4593344, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-4713693, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-4876125, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-4935533, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-5016239, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-5154887, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-5154890, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-5305935, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-562854, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-5667076, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-5833547, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-5959021, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-924676, http://linkedlifedata.com/resource/pubmed/commentcorrection/562853-985808
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0019-9567
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
377-85
pubmed:dateRevised
2010-9-2
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Mycoplasma-dependent activation of normal lymphocytes: induction of a lymphocyte-mediated cytotoxicity for allogeneic and syngeneic mouse target cells.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.