Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1-2
|
| pubmed:dateCreated |
1977-10-20
|
| pubmed:abstractText |
Population kinetics of Ehrlich ascites tumor cells grown in vivo were studied following treatment with methylglyoxal-bis(guanylhydrazone) (MeGAG; NSC-32946), a potent chemotherapeutic agent and a specific polyamine synthesis inhibitor. MeGAG-treatment resulted in a continuous accumulation of cells in the S and G2 phases of the cell cycle, and, as a consequence, the rate of cell proliferation decreased. This finding emphasizes the importance of the polyamines for progression through the cell cycle.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0304-3835
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
3
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
59-63
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:560907-Adenosylmethionine Decarboxylase,
pubmed-meshheading:560907-Animals,
pubmed-meshheading:560907-Carcinoma, Ehrlich Tumor,
pubmed-meshheading:560907-Cell Division,
pubmed-meshheading:560907-DNA, Neoplasm,
pubmed-meshheading:560907-Guanidines,
pubmed-meshheading:560907-Kinetics,
pubmed-meshheading:560907-Mitoguazone
|
| pubmed:year |
1977
|
| pubmed:articleTitle |
Population kinetics of an Ehrlich ascites tumor following treatment with methylglyoxal-bis(guanylhydrazone), a polyamine synthesis inhibitor.
|
| pubmed:publicationType |
Journal Article
|