Linked Life Data

5579666

Source:http://linkedlifedata.com/resource/pubmed/id/5579666

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1971-7-22
pubmed:abstractText
1. In anaesthetized cats, the efferent discharge recorded from slips of otherwise intact sinus nerves was sparse in eupnoeic conditions but increased markedly during systemic hypoxia or asphyxia or following the injection of cyanide or acetaldehyde into the circulation of the ipsilateral carotid body.2. When the sinus nerve was cut distal to the efferent slip the responses to cyanide or acetaldehyde were abolished. The sparse ;resting' activity which remained was increased following the intravenous injection of adrenaline. Following distal section, the impulse traffic of the efferent slip did increase during systemic hypoxia but the response was much feebler than when the nerve was otherwise intact.3. The impulse activity of most efferent slips, peeled off from the otherwise intact sinus nerve, was abolished when the glossopharyngeal nerve was cut central to its junction with the same sinus nerve, indicating that the activity was probably recorded from genuine efferent units. The discharge of some ;efferent' preparations was still present, however, following such section and showed an increase to local injections of cyanide. This activity was probably recorded from looping or branching chemoreceptor afferents.4. The discharge of efferent slips of the cut aortic nerve was increased following the intravenous injection of adrenaline and during systemic hypoxia. These responses were not present when the vagus nerve was cut central to the nodose ganglion.5. In eupnoea, chemoreceptor afferent activity recorded from slips of the sinus or aortic nerves is much the same whether these nerves be otherwise intact or whether they be cut. During systemic hypoxia, chemoreceptor afferent discharge was less when it was recorded from the otherwise intact nerves than when these nerve trunks were cut.6. The cell bodies of sinus nerve efferent fibres are synaptically excited by chemoreceptor afferents coursing in the same nerve trunk. The increase of efferent impulse activity aroused by this means depresses chemoreceptor afferent discharge.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/5579666-13192758, http://linkedlifedata.com/resource/pubmed/commentcorrection/5579666-13266504, http://linkedlifedata.com/resource/pubmed/commentcorrection/5579666-13367873, http://linkedlifedata.com/resource/pubmed/commentcorrection/5579666-14448948, http://linkedlifedata.com/resource/pubmed/commentcorrection/5579666-4298197, http://linkedlifedata.com/resource/pubmed/commentcorrection/5579666-5357227, http://linkedlifedata.com/resource/pubmed/commentcorrection/5579666-5499750, http://linkedlifedata.com/resource/pubmed/commentcorrection/5579666-5499751, http://linkedlifedata.com/resource/pubmed/commentcorrection/5579666-5579648, http://linkedlifedata.com/resource/pubmed/commentcorrection/5579666-5652880, http://linkedlifedata.com/resource/pubmed/commentcorrection/5579666-5764398
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-3751
pubmed:author
pubmed:issnType
Print
pubmed:volume
215
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
33-47
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1971
pubmed:articleTitle
Efferent and afferent impulse activity recorded from few-fibre preparations of otherwise intact sinus and aortic nerves.
pubmed:publicationType
Journal Article