Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1971-6-7
pubmed:abstractText
The penetration of (14)C-labeled ethylene glycol, erythritol, mannitol, and sucrose was measured in giant axons of various diameters isolated from the hindmost stellar nerves of Doryteuthis plei squid. Axon diameter depends mainly on the age of the squid. The influx of (22)Na, some electrical properties, and the ultrastructure of the axolemma were also studied. The results confirm our previous observation that in medium sized axons of D. plei stimulation causes an increase in the permeability to the penetration of erythritol, mannitol, and sucrose. They also demonstrate that the magnitude of the increase in the penetration of these probing molecules diminishes progressively as the axon diameter increases. The diminution in permeability may be due to a reduction in size of the pathways used by nonelectrolytes to enter the axon. No effect of stimulation on the ethylene glycol permeability is observed. The sodium influx and electrical properties are independent of axon size. The ultrastructural study shows that the axolemma thickness increases with axon diameter. The present experiments indicate that the nonelectrolyte permeability of stimulated axons depends on nerve fiber properties related to axon diameter and on the size of the hydrophilic nonelectrolyte probe.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/5553105-13271727, http://linkedlifedata.com/resource/pubmed/commentcorrection/5553105-13889814, http://linkedlifedata.com/resource/pubmed/commentcorrection/5553105-13997307, http://linkedlifedata.com/resource/pubmed/commentcorrection/5553105-13997308, http://linkedlifedata.com/resource/pubmed/commentcorrection/5553105-14328451, http://linkedlifedata.com/resource/pubmed/commentcorrection/5553105-14861788, http://linkedlifedata.com/resource/pubmed/commentcorrection/5553105-14861789, http://linkedlifedata.com/resource/pubmed/commentcorrection/5553105-4231736, http://linkedlifedata.com/resource/pubmed/commentcorrection/5553105-5229832, http://linkedlifedata.com/resource/pubmed/commentcorrection/5553105-5500991, http://linkedlifedata.com/resource/pubmed/commentcorrection/5553105-5654761, http://linkedlifedata.com/resource/pubmed/commentcorrection/5553105-5971032
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-1295
pubmed:author
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
623-37
pubmed:dateRevised
2010-6-22
pubmed:meshHeading
pubmed:year
1971
pubmed:articleTitle
Nonelectrolyte permeability, sodium influx, electrical potentials, and axolemma ultrastructure in squid axons of various diameters.
pubmed:publicationType
Journal Article