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pubmed:abstractText |
In 12 of 128 patients with Hodgkin's disease (10%) haemolytic anaemia could be observed. In 3 of 12 patients an (auto-)immunological etiology of haemolysis was proven by the positive antiglobulin-test. In the rest of patients (9 of 12) the haemolytic syndrome could be explained by the concomitant enlargement of the spleen. In addition to high-dose prednisolone, splenectomy is the method of choice for the treatment of the haemolytic syndrome (4 of 6 patients). If adequate treatment of Hodgkin's disease is provided, the disease (2--37 months) will not be influenced by haemolytic anaemia.
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