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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1976-3-30
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pubmed:abstractText |
A radioimmune assay (RIA) method for detecting heterologous serum rabbit gamma-globulin (RG) and antibody to this protein is described. The methodology is used for monitoring serum levels of rabbit globulin in patients receiving rabbit ATG (RATG). In 7 cardiac recipients receiving RATG, maximum serum levels of RG were achieved 1-3 days after administration of final dose. RG half-life subsequent to peak serum levels was rapid (X = 36 hr) in 4 patients and prolonged (X = 18 days) in 3 patients. Patient antibody to rabbit gamma-globulin was detectable only in those patients with short RG half-life. Antirabbit antibody titers in these patients were extremely low and barely detectable by RIA.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0041-1337
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
393-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:54964-Animals,
pubmed-meshheading:54964-Antibodies, Anti-Idiotypic,
pubmed-meshheading:54964-Antibody Formation,
pubmed-meshheading:54964-Antigens,
pubmed-meshheading:54964-Antigens, Heterophile,
pubmed-meshheading:54964-Antilymphocyte Serum,
pubmed-meshheading:54964-Heart Transplantation,
pubmed-meshheading:54964-Hemagglutination Tests,
pubmed-meshheading:54964-Humans,
pubmed-meshheading:54964-Rabbits,
pubmed-meshheading:54964-Radioimmunoassay,
pubmed-meshheading:54964-Sheep,
pubmed-meshheading:54964-T-Lymphocytes,
pubmed-meshheading:54964-Time Factors,
pubmed-meshheading:54964-Transplantation, Homologous,
pubmed-meshheading:54964-gamma-Globulins
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pubmed:year |
1975
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pubmed:articleTitle |
Radioimmune assay of heterologous serum gamma-globulin in patients receiving rabbit antihuman thymocyte globulin.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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