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pubmed:otherAbstract |
PIP: Endometrial changes in 105 women taking a variety of oral contraceptive pills for periods ranging from 2 to 60 months were studied. Individual response, as measured by endometrial change, varied greatly. Among the changes noted were: 1) atrophic proliferative glands with hypertrophic decidual stroma; 2) nodular stromal hyperplasia; 3) myometrial hyperplasia; 4) capillary thickening with endothelial proliferation and fibrin thrombi; 5) increased lymphatics simulating micorcysts; and 6) atypical hyperplasia of decidual cells. Endometrial stromal reaction seemed greatest in women who had taken pills for the longest time.
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