Linked Life Data

541154

Source:http://linkedlifedata.com/resource/pubmed/id/541154

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1980-6-27
pubmed:abstractText
41 226 isoniazid exposed and 22 811 non-exposed patients admitted to Canadian institutions for the treatment of tuberculosis from 1952 to 1960 were followed to 1973 by computerised record linkage to the National Death Index and, for 1969 to 1973, to the National Cancer Incidence Reporting System; The mortality for the total cohort compared to that expected from the mortality in the Canadian population, was greater than expected for tuberculosis, other chest diseases and certain cancer sites associated with cigarette smoking (except bladder cancer). There was, however, no difference between the isoniazid-exposed and non-exposed in mortality from all cancer and individual cancer sites, except for oesophageal cancer in males. Cancer incidence from 1969 to 1973 was also similar for the isoniazid- exposed and non-exposed groups. An elevated standardised incidence ratio was seen only for buccal cavity and pharynx in male exposed subjects. It is concluded that this study provides additional negative evidence on the carcinogenicity of isoniazid in man.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0300-5771
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
305-12
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Isoniazid exposure in relation to cancer incidence and mortality in a cohort of tuberculosis patients.
pubmed:publicationType
Journal Article