Linked Life Data

533223

Source:http://linkedlifedata.com/resource/pubmed/id/533223

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1980-4-23
pubmed:abstractText
The distributions of within-person variances in the concentrations of 10 commonly assayed serum constituents have been derived from data on 37 healthy male subjects studied at weekly intervals over a period of five months. All 10 distributions appear to be of log-normal form. The relevance of the findings to the interpretation of differences between serial measurements in a given individual is discussed. Examples are given to show how the information on within-person variances for a particular analyte, organised into a simple graph, may be used to test medical opinions on threshold values for serial changes in the concentration of this analyte in a given individual. In this way, biological variability as well as analytical error may be taken into account quantitatively when assessing the significance of a difference between two serial measurements.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0004-5632
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
169-76
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Temporal changes in the concentrations of serum constituents in healthy men. Distributions of within-person variances and their relevance to the interpretation of differences between successive measurements.
pubmed:publicationType
Journal Article