Linked Life Data

5291754

Source:http://linkedlifedata.com/resource/pubmed/id/5291754

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1972-7-17
pubmed:abstractText
The efficacy of horizontal and vertical laminar flow units (equipped with high-efficiency air filters) in the prevention of cross-contamination between cages and of contamination from outside has been demonstrated. With germ-free mice and using germ-free standard techniques for sterilization and for the transfer of germ-free mice into the cabinets via a standard entry lock, it was found that during an observation period of 2 weeks the animals remain ;negative'. Other experiments were performed with equally good results in cabinets equipped with a hinged flap, closing 95% of the open front side. When the flap was closed the air flow could be reduced accordingly, thus reducing the noise level and the risk of dehydration.Experiments made with germ-free mice in a ;down-flow unit' were also invariably good.In another type of experiment, cages with conventional mice were placed in the cabinets between cages with germ-free animals at varying distances. If all animals were maintained on wire mesh (to minimize the aerosol production of dust) and if the ;conventional' cages were at a distance of 10 cm. from ;germ-free cages' the latter remained bacteria-free during test periods of one week.The use of ;laminar flow isolators' for the isolation of human patients is mentioned.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0022-1724
pubmed:author
pubmed:issnType
Print
pubmed:volume
69
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
83-9
pubmed:dateRevised
2010-9-10
pubmed:meshHeading
pubmed:year
1971
pubmed:articleTitle
Prevention of airborne contamination and cross-contamination in germ-free mice by laminar flow.
pubmed:publicationType
Journal Article