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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8
|
| pubmed:dateCreated |
1980-1-28
|
| pubmed:abstractText |
The synthetic prostaglandin analogue cloprostenol has been prepared radiolabelled with 14C. The isotopic abundance of 14C at position C-15 was greater than 90% of the theoretical maximum. We have utilizted the high abundance of the 14C isotope for metabolism studies by preparing mixtures of [12C]:[14C]cloprostenol such that fragments detected by mass spectrometry contained characteristic isotope clusters analogous to those often obtained using stable isotopes.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0306-042X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
6
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
359-60
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:497363-Animals,
pubmed-meshheading:497363-Carbon Radioisotopes,
pubmed-meshheading:497363-Cloprostenol,
pubmed-meshheading:497363-Female,
pubmed-meshheading:497363-Mass Spectrometry,
pubmed-meshheading:497363-Prostaglandins F, Synthetic,
pubmed-meshheading:497363-Rats,
pubmed-meshheading:497363-Technology, Pharmaceutical,
pubmed-meshheading:497363-Trimethylsilyl Compounds
|
| pubmed:year |
1979
|
| pubmed:articleTitle |
Ion cluster techniques in drug metabolism: an example of the use of mixtures of the [12C]:[14C] isotopic forms of the synthetic prostaglandin cloprostenol ('Estrumate') to facilitate metabolite identification.
|
| pubmed:publicationType |
Journal Article
|