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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1979-12-27
|
| pubmed:abstractText |
Porcine elastase II (EC 3.4.21.-), a pancreatic proteinase with elastolytic activity, hydrolyses the oxidized beta-chain of insulin with major cleavages occurring at Leu17-Val18, Phe24-Phe25, Phe25-Tyr26 and Tyr26-Thr27. Canine leucocytic elastase splits the same substrate with major sites at Val12-Glu13 and Val18-Cys19 O3H. This indicates similarity of elastase II to chymotrypsins (EC 3.4.21.1 or 3.4.21.2) and of dog leucocyte enzyme to human granulocyte elastase and porcine pancreatic elastase I (EC 3.4.21.11).
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0001-527X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
26
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
267-73
|
| pubmed:dateRevised |
2011-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:494946-Amino Acid Sequence,
pubmed-meshheading:494946-Animals,
pubmed-meshheading:494946-Dogs,
pubmed-meshheading:494946-Insulin,
pubmed-meshheading:494946-Leukocytes,
pubmed-meshheading:494946-Macromolecular Substances,
pubmed-meshheading:494946-Pancreas,
pubmed-meshheading:494946-Pancreatic Elastase,
pubmed-meshheading:494946-Substrate Specificity
|
| pubmed:year |
1979
|
| pubmed:articleTitle |
Specificity of elastases: degradation of the oxidized beta-chain of insulin by porcine pancreatic elastase II and dog leucocyte elastase.
|
| pubmed:publicationType |
Journal Article
|