Linked Life Data

490329

Source:http://linkedlifedata.com/resource/pubmed/id/490329

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1979-12-20
pubmed:abstractText
Low concentrations of procaine (10(-5) M) are capable of provoking changes in the membrane potential of snail neurons. This effect is produced by direct application to the membrane and is characterized by a short response time and rapid reversibility. The resulting potential change has the same properties as that which follows acetylcholine application, including the same change of membrane resistance, the same relationship with membrane potential, the same ionic dependence and, finally, the same pharmacological sensitivity. The identity between the acetylcholine and procaine responses holds both for cells depolarized and cells hyperpolarized by acetylcholine. This procaine sensitivity involves only about two-thirds of the cells and it is concluded that procaine activates the cholinergic receptor on these cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0022-3565
pubmed:author
pubmed:issnType
Print
pubmed:volume
211
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
93-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Procaine as an acetylcholine agonist in snail neuron.
pubmed:publicationType
Journal Article, In Vitro