Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1968-8-2
pubmed:abstractText
The cationic antibacterial proteins of rabbit PMN lysosomes have been resolved into at least five subfractions. Each of these showed substantial selectivity in its antibacterial action against several pathogenic bacteria, including two smooth and two rough Escherichia coli strains, three Staphylococcus aureus strains, one S. albus, three proteus species and four different cultures of streptococcus. Each of the subfractions possesses a different electrophoretic mobility. Amino acid analyses of the three most cationic components revealed high contents of arginine consistent with their relative electrophoretic mobilities and very high arginine to lysine ratios. Aromatic amino acids were present in very low concentrations in these proteins and their light absorption at 2800 A was correspondingly weak. The evidence of antibacterial specificity, along with marked differences in the arginine-lysine ratios, shows that the cationic antibacterial components of rabbit PMN lysosomes are biologically and chemically heterogeneous.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-13376807, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-13488885, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-13694490, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-14068232, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-14247717, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-14275408, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-14907713, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-4161205, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-4162449, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-4163887, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-4379082, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-4958495, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-5904408, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-5926298, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-5927898, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-5934973, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-5934974, http://linkedlifedata.com/resource/pubmed/commentcorrection/4871738-6021205
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-1007
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
127
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
927-41
pubmed:dateRevised
2010-6-22
pubmed:meshHeading
pubmed:year
1968
pubmed:articleTitle
Arginine-rich proteins of polymorphonuclear leukocyte lysosomes. Antimicrobial specificity and biochemical heterogeneity.
pubmed:publicationType
Journal Article