Linked Life Data

4833576

Source:http://linkedlifedata.com/resource/pubmed/id/4833576

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1974-7-31
pubmed:abstractText
Likelihood methods are developed for the estimation and testing of multiple-locus gametic disequilibria, using log-linear models of parametric effects. The estimates of disquilibrium are related to Kimura's Z-measure, and may be extended to multiple alleles and multiple loci. Likelihood ratio test criteria are constructed, which are asymptotically distributed as chi(2). The analysis is partitioned into various components corresponding to two-locus, residual three-locus, and higher order disequilibria. A four-locus example from Hordeum vulgare L. is utilized to illustrate the analysis. Most of the multiple-locus disequilibrium is accounted for by two-locus effects, and closely linked loci show considerably more disequilibrium than unlinked loci. It is shown that all possible pairwise comparisons are not statistically independent.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0016-6731
pubmed:author
pubmed:issnType
Print
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
557-65
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1974
pubmed:articleTitle
Likelihood analysis of recombinational disequilibrium in multiple-locus gametic frequencies.
pubmed:publicationType
Journal Article