|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1973-12-14
|
|
pubmed:abstractText |
BALB/c mice born to and nursed by females immunized against MSV-M showed a reduced tumour incidence and a high tumour regression rate following MSV-M injection at 7-14 days of age. Females immunized long before mating could also confer protection to their offspring whereas females immunized after parturition could not. A reduced number of tumours was observed in 3 out of 14 MSV-M injected litters whose mothers had been previously exposed to the virus while nursing infected offspring. Sera from suckling mice born to and nursed by immunized mothers contained MSV-M neutralizing antibody as shown by an in vitro focus reduction assay. Cell-free extracts from mice which developed leukaemia after MSV-M inoculation were tested for oncogenic activity in 1-week old mice. Out of 6 extracts, 4 induced typical MSV-M tumours and 2 caused leukaemias.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-4290556,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-4296210,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-4301109,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-4310638,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-4333859,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-4734119,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-4860892,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-4867925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-4876979,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-4899685,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-4904707,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-4944746,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-5219685,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-5435899,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-5530559,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-5659629,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-5765223,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-5781092,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4795530-5922129
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0007-0920
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
28
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
238-44
|
|
pubmed:dateRevised |
2011-7-20
|
|
pubmed:meshHeading |
pubmed-meshheading:4795530-Animals,
pubmed-meshheading:4795530-Female,
pubmed-meshheading:4795530-Immunization,
pubmed-meshheading:4795530-Leukemia, Experimental,
pubmed-meshheading:4795530-Maternal-Fetal Exchange,
pubmed-meshheading:4795530-Mice,
pubmed-meshheading:4795530-Mice, Inbred BALB C,
pubmed-meshheading:4795530-Moloney murine leukemia virus,
pubmed-meshheading:4795530-Neutralization Tests,
pubmed-meshheading:4795530-Pregnancy,
pubmed-meshheading:4795530-Sarcoma, Experimental
|
|
pubmed:year |
1973
|
|
pubmed:articleTitle |
Prevention of murine sarcoma virus oncogenesis in offspring of immunized female mice.
|
|
pubmed:publicationType |
Journal Article
|
