Linked Life Data

47239

Source:http://linkedlifedata.com/resource/pubmed/id/47239

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1975-6-12
pubmed:abstractText
A method for the ultrastructural demonstration of cystine in keratinized epidermal cells of guinea pig back hairy skin is described. This involves selective oxidation by peracetic acid and formation of an electron dense reaction product with uranyl acetate. Unkeratinized cells were unstained except for nuclei and keratohyalin. The thickened plasma membranes of transitional and keratinized cells were darkly stained. In transitional keratinized cells darkly stained membranes occurred initially in relation to desmosomes and then spread to intervening membrane areas. Dense material, probably matrix keratin containing cystine was found in the interiors of basal horny cells but not in the intermediate or superificial cells of the stratum corneum. It is suggested that the unstable matrix keratin is probably broken down by enzymatic hydrolysis above the basal zone of the stratum corneum.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0003-9187
pubmed:author
pubmed:issnType
Print
pubmed:volume
251
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
289-94
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Ultrastructural demonstration of cystine in guinea pig back stratum corneum.
pubmed:publicationType
Journal Article