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rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
2
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pubmed:dateCreated |
1975-5-27
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|
pubmed:abstractText |
Neonatal liver or adult spleen was used as a source of B-lymphocytes in reconstituting lethally irradiated, syngeneic mice. Recipients were all given excess adult, syngeneic thymus cells and were immunized with dinitrophenylated bovine gamma globulin. The distribution of avidities of plaque-forming cells produced by immunized recipients of neonatal liver was highly restricted in comparison with animals reconstituted with adult spleen indicating a restriction of B-lymphocyte heterogeneity in the neonatal mouse.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Feb
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|
pubmed:issn |
0014-9446
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
34
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
151-2
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:46833-Animals,
pubmed-meshheading:46833-Animals, Newborn,
pubmed-meshheading:46833-Antibody Specificity,
pubmed-meshheading:46833-B-Lymphocytes,
pubmed-meshheading:46833-Epitopes,
pubmed-meshheading:46833-Haptens,
pubmed-meshheading:46833-Hemolytic Plaque Technique,
pubmed-meshheading:46833-Immunity, Cellular,
pubmed-meshheading:46833-Immunity, Maternally-Acquired,
pubmed-meshheading:46833-Immunization, Passive,
pubmed-meshheading:46833-Liver,
pubmed-meshheading:46833-Mice,
pubmed-meshheading:46833-Nitrobenzenes,
pubmed-meshheading:46833-Radiation Chimera,
pubmed-meshheading:46833-Spleen,
pubmed-meshheading:46833-Transplantation, Homologous,
pubmed-meshheading:46833-gamma-Globulins
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pubmed:year |
1975
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|
pubmed:articleTitle |
Ontogeny of B-lymphocyte function with respect to the heterogeneity of antibody affinity-1,2.
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|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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