|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0000677,
umls-concept:C0001811,
umls-concept:C0012655,
umls-concept:C0025914,
umls-concept:C0026809,
umls-concept:C0205246,
umls-concept:C0332291,
umls-concept:C0439662,
umls-concept:C0442805,
umls-concept:C0449438,
umls-concept:C0596263,
umls-concept:C1123023
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|
pubmed:issue |
4121
|
|
pubmed:dateCreated |
1974-2-14
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|
pubmed:abstractText |
The dependence of chemical carcinogenesis on age of target tissue was studied by repeated DMBA-treatment of mouse skin grafted from old and young syngeneic donors to young recipients. Carcinomas developed on 39 percent (1.6/41) of grafts from old donors and on 12 percent (5/41) of grafts from young donors. The incidence of nonskin lymphoid tumors was highest in male recipients bearing grafts from old donors.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
0036-8075
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
18
|
|
pubmed:volume |
183
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
217-8
|
|
pubmed:dateRevised |
2009-4-1
|
|
pubmed:meshHeading |
pubmed-meshheading:4587442-Age Factors,
pubmed-meshheading:4587442-Aging,
pubmed-meshheading:4587442-Animals,
pubmed-meshheading:4587442-Benz(a)Anthracenes,
pubmed-meshheading:4587442-Carcinoma,
pubmed-meshheading:4587442-Female,
pubmed-meshheading:4587442-Leukemia, Lymphoid,
pubmed-meshheading:4587442-Lymphoma, Large B-Cell, Diffuse,
pubmed-meshheading:4587442-Male,
pubmed-meshheading:4587442-Mice,
pubmed-meshheading:4587442-Mice, Inbred BALB C,
pubmed-meshheading:4587442-Neoplasm Transplantation,
pubmed-meshheading:4587442-Papilloma,
pubmed-meshheading:4587442-Sex Factors,
pubmed-meshheading:4587442-Skin Neoplasms,
pubmed-meshheading:4587442-Skin Transplantation,
pubmed-meshheading:4587442-Tissue Donors,
pubmed-meshheading:4587442-Transplantation, Homologous
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|
pubmed:year |
1974
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|
pubmed:articleTitle |
Aging increases susceptibility of mouse skin to DMBA carcinogenesis independent of general immune status.
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|
pubmed:publicationType |
Journal Article
|
