Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1980-4-17
pubmed:abstractText
Renal function, fluoride formation and excretion were studied during and after enflurane anaesthesia in seven patients. During anaesthesia, urine flow rate, inulin clearance, PAH clearance and fractional sodium excretion were 13, 78, 65 and 49% of control values, respectively. Renal function was promptly restored postoperatively. Enflurane was metabolized to inorganic fluoride with a mean maximal serum level of 17.4 +/- 3.3 microM. Fractional fluoride excretion decreased during anaesthesia to 35% of the control value. Postoperatively, there was a highly significant correlation between the increase in fractional fluoride excretion and the rise in urinary pH during two consecutive 3-hour periods. It is suggested that tubular reabsorption of fluoride is inversely related to tubular fluid pH and that fluoride is reabsorbed by non-ionic diffusion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0515-2720
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
20-3
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Fluoride kinetics and renal function during enflurane anaesthesia.
pubmed:publicationType
Journal Article