| pubmed-article:4343974 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:4343974 | lifeskim:mentions | umls-concept:C0012854 | lld:lifeskim |
| pubmed-article:4343974 | lifeskim:mentions | umls-concept:C0004793 | lld:lifeskim |
| pubmed-article:4343974 | lifeskim:mentions | umls-concept:C0014230 | lld:lifeskim |
| pubmed-article:4343974 | lifeskim:mentions | umls-concept:C0443288 | lld:lifeskim |
| pubmed-article:4343974 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:4343974 | pubmed:dateCreated | 1973-1-29 | lld:pubmed |
| pubmed-article:4343974 | pubmed:abstractText | The sequence of DNA base pairs adjacent to the phosphodiester bonds cleaved by the RI restriction endonuclease in unmodified DNA from coliphage lambda has been determined. The 5'-terminal nucleotide labeled with (32)P and oligonucleotides up to the heptamer were analyzed from a pancreatic DNase digest. The following sequence of nucleotides adjacent to the RI break made in lambda DNA was deduced from these data and from the 3'-dinucleotide sequence and nearest-neighbor analysis obtained from repair synthesis with the DNA polymerase of Rous sarcoma virus [Formula: see text] The RI endonuclease cleavage of the phosphodiester bonds (indicated by arrows) generates 5'-phosphoryls and short cohesive termini of four nucleotides, (p)A(p)A(p)T(p)T. The most striking feature of the sequence is its symmetry. | lld:pubmed |
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| pubmed-article:4343974 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:4343974 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:4343974 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:4343974 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:4343974 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:4343974 | pubmed:author | pubmed-author:GoodmanH MHM | lld:pubmed |
| pubmed-article:4343974 | pubmed:author | pubmed-author:HedgpethJJ | lld:pubmed |
| pubmed-article:4343974 | pubmed:author | pubmed-author:BoyerH WHW | lld:pubmed |
| pubmed-article:4343974 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:4343974 | pubmed:volume | 69 | lld:pubmed |
| pubmed-article:4343974 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:4343974 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:4343974 | pubmed:pagination | 3448-52 | lld:pubmed |
| pubmed-article:4343974 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:4343974 | pubmed:year | 1972 | lld:pubmed |
| pubmed-article:4343974 | pubmed:articleTitle | DNA nucleotide sequence restricted by the RI endonuclease. | lld:pubmed |
| pubmed-article:4343974 | pubmed:publicationType | Journal Article | lld:pubmed |
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