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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
37
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pubmed:dateCreated |
1978-3-10
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pubmed:abstractText |
The cerebrospinal fluid of 120 subjects, 80 of whom were suffering from a purulent meningitis, were examined comparatively by classical bacteriological techniques (direct examination and culture) and by electro-immunodiffusion. This procedure makes it possible to detect not only viable bacteria, but also capsular polysaccharide antigens. It revealed the diagnosis in 96.9% of cases of meningococcal, pneumococcal and Haemophilus meningitis, as against 80.3% positive results using classical bacteriological techniques, for the same organisms. Electro-immunodiffusion provides a rapid answer (20 minutes) and, amongst other things, makes it possible: - to confirm the serotype or capsular type within the species, - to determine the aetiological diagnosis in certain types of meningitis where diagnosis is rendered difficult by blind antibiotic therapy, - to quantify and follow over a period of time the levels of polysaccharide antigens in the cerebrospinal fluid and serum of the patients. The sensitivity and specificity of electro-immunodiffusion render it a technique of the future in the diagnosis of purulent meningitis. By virtue of its simplicity, it should become a routine examination.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0301-1518
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
5
|
pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3391-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:414201-Antigens, Bacterial,
pubmed-meshheading:414201-Counterimmunoelectrophoresis,
pubmed-meshheading:414201-Humans,
pubmed-meshheading:414201-Immunodiffusion,
pubmed-meshheading:414201-Meningitis,
pubmed-meshheading:414201-Meningitis, Haemophilus,
pubmed-meshheading:414201-Meningitis, Meningococcal,
pubmed-meshheading:414201-Meningitis, Pneumococcal,
pubmed-meshheading:414201-Serotyping
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pubmed:year |
1977
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pubmed:articleTitle |
[The rapid detection and specific identification of bacterial antigens by electro-immunodiffusion in 80 cases of purulent meningitis (author's transl)].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|