pubmed-article:411380 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:411380 | lifeskim:mentions | umls-concept:C0221102 | lld:lifeskim |
pubmed-article:411380 | lifeskim:mentions | umls-concept:C0008810 | lld:lifeskim |
pubmed-article:411380 | lifeskim:mentions | umls-concept:C1524119 | lld:lifeskim |
pubmed-article:411380 | lifeskim:mentions | umls-concept:C0032821 | lld:lifeskim |
pubmed-article:411380 | pubmed:issue | 5 | lld:pubmed |
pubmed-article:411380 | pubmed:dateCreated | 1977-12-29 | lld:pubmed |
pubmed-article:411380 | pubmed:abstractText | Conscious chair-acclimatized squirrel monkeys (Saimiri sciureus) studied with lights on (600 lx) from 0800 to 2000 h daily (LD 12:12) display a prominent circadian rhythm in renal potassium excretion. The characteristics of this rhythm were reproduced in adrenalectomized monkeys by infusing 5 mg cortisol and 0.001 mg aldosterone, or 5 mg cortisol alone, between 0800 and 0900 h daily. When the timing of cortisol adminisration (with or without aldosterone) was phase-delayed by 8 h, the urinary potassium rhythm resynchronized by 80% of the cortisol phase shift, but only after a transient response lasting 3-4 days. With the same daily dose of adrenal steroids given as a continuous infusion throughout each 24 h, urinary potassium excretion showed free-running oscillations no longer synchronized to the light-dark cycle. These results indicate that the cirdacian rhythm of plasma cortisol concentration acts as an internal mediator in the circadian timing system, synchronizing a potentially autonomous oscillation in renal potassium excretion to environmental time cues and to other circadian rhythms within the animal. | lld:pubmed |
pubmed-article:411380 | pubmed:language | eng | lld:pubmed |
pubmed-article:411380 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:411380 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:411380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:411380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:411380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:411380 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:411380 | pubmed:month | Nov | lld:pubmed |
pubmed-article:411380 | pubmed:issn | 0002-9513 | lld:pubmed |
pubmed-article:411380 | pubmed:author | pubmed-author:HerdJ AJA | lld:pubmed |
pubmed-article:411380 | pubmed:author | pubmed-author:KassD ADA | lld:pubmed |
pubmed-article:411380 | pubmed:author | pubmed-author:SchmelzerW... | lld:pubmed |
pubmed-article:411380 | pubmed:author | pubmed-author:Moore-edeM... | lld:pubmed |
pubmed-article:411380 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:411380 | pubmed:volume | 233 | lld:pubmed |
pubmed-article:411380 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:411380 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:411380 | pubmed:pagination | R230-8 | lld:pubmed |
pubmed-article:411380 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:411380 | pubmed:meshHeading | pubmed-meshheading:411380-S... | lld:pubmed |
pubmed-article:411380 | pubmed:year | 1977 | lld:pubmed |
pubmed-article:411380 | pubmed:articleTitle | Cortisol-mediated synchrinization of circadian rhythm in urinary potassium excretion. | lld:pubmed |
pubmed-article:411380 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:411380 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:411380 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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