Linked Life Data

406775

Source:http://linkedlifedata.com/resource/pubmed/id/406775

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1977-8-12
pubmed:abstractText
Intravenous infusion of glucose-amino acid complexes, formed during heat sterilization of mixtures of glucose and amino acids or protein hydrolysates, has been associated with mild dehydration in infants, and with excessive trace metal ion excretion in both infants and adults. When parenteral solutions containing these glucose-amino acid complexes were infused into pregnant rhesus monkeys, the compounds accumlated in the maternal plasma and were transported to the fetal circulation. Although all of the compounds studied crossed the placenta, fetal levels were consistently lower than maternal levels. Amniotic fluid concentrations of these compounds increased progressively with the length of maternal infusion, presumably through fetal urination into the amniotic sac. In animals infused with solutions not heat sterilized, levels of these compounds could not be detected in maternal plasma and urine, fetal plasma and urine, or in amniotic fluid. In view of possible toxicity of the glucose-amino acid complexes, parenteral solutions containing these compounds should probably be avoided in the intravenous nutrition of the pregnant woman.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0002-9165
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1087-93
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Placental transfer of glucose-amino acid complexes present in parenteral solutions.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.