pubmed-article:4025512 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:4025512 | lifeskim:mentions | umls-concept:C0013366 | lld:lifeskim |
pubmed-article:4025512 | lifeskim:mentions | umls-concept:C0040184 | lld:lifeskim |
pubmed-article:4025512 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
pubmed-article:4025512 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:4025512 | pubmed:dateCreated | 1985-9-24 | lld:pubmed |
pubmed-article:4025512 | pubmed:abstractText | The role of chondroclasts in the pathogenesis of Fusarium roseum-induced tibial dyschondroplasia (TD) was examined in a histomorphometric study. TD developed rapidly in broiler chickens placed at 1 day of age on rations containing either 3% (Experiment 1) or 2% (Experiment 2) F roseum cultures. In Experiment 1 the frequency of TD in birds killed at 4 weeks of age was 90%. In Experiment 2, birds were killed at intervals from 4 days until 4 weeks of age. By 1 week of age, 70% of birds examined had characteristic accumulations of prehypertrophic cartilage at the proximal tibial physis, and the frequency of TD in 4-week-old birds was 80%. Sections of hypertrophic cartilage from F roseum-fed and control birds from both experiments were examined for determination of the volume density of chondroclasts along the vascular channel boundary. Chondroclast density was consistently lower in F roseum-fed than in control birds, but the difference was significant only at 4 weeks of age. The fact that gross lesions were evident before a significant decrease in chondroclast density occurred indicates that a decrease in the density of chondroclasts was not an essential factor in the accumulation of cartilage characteristic of TD. | lld:pubmed |
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pubmed-article:4025512 | pubmed:language | eng | lld:pubmed |
pubmed-article:4025512 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:4025512 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:4025512 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:4025512 | pubmed:month | Aug | lld:pubmed |
pubmed-article:4025512 | pubmed:issn | 0002-9440 | lld:pubmed |
pubmed-article:4025512 | pubmed:author | pubmed-author:FletcherT FTF | lld:pubmed |
pubmed-article:4025512 | pubmed:author | pubmed-author:LawlerE MEM | lld:pubmed |
pubmed-article:4025512 | pubmed:author | pubmed-author:WalserM MMM | lld:pubmed |
pubmed-article:4025512 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:4025512 | pubmed:volume | 120 | lld:pubmed |
pubmed-article:4025512 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:4025512 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:4025512 | pubmed:pagination | 276-81 | lld:pubmed |
pubmed-article:4025512 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:4025512 | pubmed:year | 1985 | lld:pubmed |
pubmed-article:4025512 | pubmed:articleTitle | Chondroclasts in fusarium-induced tibial dyschondroplasia. A histomorphometric study. | lld:pubmed |
pubmed-article:4025512 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:4025512 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
pubmed-article:4025512 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |