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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1985-9-24
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pubmed:abstractText |
The role of chondroclasts in the pathogenesis of Fusarium roseum-induced tibial dyschondroplasia (TD) was examined in a histomorphometric study. TD developed rapidly in broiler chickens placed at 1 day of age on rations containing either 3% (Experiment 1) or 2% (Experiment 2) F roseum cultures. In Experiment 1 the frequency of TD in birds killed at 4 weeks of age was 90%. In Experiment 2, birds were killed at intervals from 4 days until 4 weeks of age. By 1 week of age, 70% of birds examined had characteristic accumulations of prehypertrophic cartilage at the proximal tibial physis, and the frequency of TD in 4-week-old birds was 80%. Sections of hypertrophic cartilage from F roseum-fed and control birds from both experiments were examined for determination of the volume density of chondroclasts along the vascular channel boundary. Chondroclast density was consistently lower in F roseum-fed than in control birds, but the difference was significant only at 4 weeks of age. The fact that gross lesions were evident before a significant decrease in chondroclast density occurred indicates that a decrease in the density of chondroclasts was not an essential factor in the accumulation of cartilage characteristic of TD.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-1113513,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-1164313,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-1164315,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-1164316,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-14312578,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-204011,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-233597,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-233598,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-4129060,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-4989821,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-5080204,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-5107295,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-6681256,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-6996305,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-7013463,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-7147613,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-7447833,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4025512-843305
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0002-9440
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
120
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
276-81
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1985
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pubmed:articleTitle |
Chondroclasts in fusarium-induced tibial dyschondroplasia. A histomorphometric study.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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