Linked Life Data

4021305

Source:http://linkedlifedata.com/resource/pubmed/id/4021305

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1985-8-23
pubmed:abstractText
The authors studied the action of the physiological concentrations of catecholamines on the major parameters of the action potentials of the true pacemakers, using a graphic analysis of their electric activity at the intracellular microelectrode lead. Desympathization was carried out with the help of daily intraperitoneal injections of guanethidine solution for six weeks. Noradrenaline and dopamine have a similar effect on the electrogenesis of the pacemakers by decreasing a relative threshold of auto-stimulation and decreasing the steepness of the potential growth in phase 4 on the curve of the action potential. Pharmacological desympathization leads to the development of hyper-reactivity of the true pacemakers to noradrenaline and dopamine and triggers off changes in the regulation of the electric activity of these cells by catecholamines.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-9040
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
88-93
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
[Action of noradrenaline and dopamine on the pacemaker cells of the normal rat sinus node and in pharmacological sympathectomy].
pubmed:publicationType
Journal Article, Comparative Study, In Vitro, English Abstract