Linked Life Data

4021283

Source:http://linkedlifedata.com/resource/pubmed/id/4021283

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-9-16
pubmed:abstractText
The effect of hyperglycemia on adrenergic response of the heart and coronary vessels was examined, using an alloxan diabetes model, in an experimental study involving catheterization, extracorporal perfusion and coronary arterial resistance measurement in dogs with intact thoracic cavities. Experimental diabetes mellitus was shown to be associated with enhanced positively chronotropic--and weakened negatively chrono- and inotropic--cardiac response to catecholamines introduced into the perfusion flow. Adrenergic reactive dilatation of coronary vessels was first enhanced, and later weakened, as glycemia progressed. It is assumed that a disturbance of hormonal interrelations due to insulin deficiency may play a role in the mechanism of changed adrenergic response of the heart and coronary vessels in experimental diabetes mellitus.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0022-9040
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
94-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
[Changes in the adrenergic mechanisms regulating cardiac activity and coronary circulation in experimental diabetes mellitus].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract