Linked Life Data

402038

Source:http://linkedlifedata.com/resource/pubmed/id/402038

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1977-3-31
pubmed:abstractText
Neutrophil bactericidal function (NBF) was studied in dogs during intravenous infusions of Pseudomonas aeruginosa. Administration of 10(6) bacteria per minute over 3 hours was associated with a bacteremia level of about 10(3) organisms per milliliter of blood without adverse effects on NBF. Infusion of 10(7) organisms per minute resulted in blood bacterial counts in the upper 10(4) range and significantly impaired NBF. To determine the relative contribution of the spleen in bacterial phagocytosis, splenectomies were performed in additional dogs immediately prior to 5 hour infusions of 10(6) Pseudomonas aeruginosa per minute. Results revealed that splenectomy did not influence the blood bacterial clearance. These experimental findings emphasize the dominant role of polymorphonuclear leukocytes in bacterial defense.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0039-6060
pubmed:author
pubmed:issnType
Print
pubmed:volume
81
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
180-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Effect of prolonged bacteremia on leukocyte bactericidal function.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.