Linked Life Data

4002894

Source:http://linkedlifedata.com/resource/pubmed/id/4002894

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1985-7-19
pubmed:abstractText
The new anticholinergic agent Propiverinhydrochlorid (Mictonorm) is used in the treatment of the Enuresis nocturna et diurna combined with urgency, frequency and small amounts of voided urine. The urodynamic investigation shows an unstable bladder. No urinary tract obstruction or neurogenic injuries are detected at the 26 normal-developed children of 5-11 years of age. Mictonorm was given for 3 months, in a dosage of 0,4 mg/kg bw/d. The bladder capacity, the volume at the desire to void and the compliance of the detrusor significantly increased and the frequency decreased. Application of placebo shows no variation of these parameters. No side-effects were to be distinguish. The wetting improved significantly in 16 of the 26 children but dryness seldom was reached. Therefore the dose was doubled in 19 children at the fourth month, and a second equal group of 26 children primary was treated with 0,7-0,8 mg/kg bw/d. With good compatibility especially the higher dose given from the beginning improved the enuresis better. All children showed a more distinct influence to the enuresis diurna than to the nocturna. The prescription of the anticholinergic neurotrope and myotrope drug is interpreted as a part of the management of the wetting child and its environment.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0044-3611
pubmed:author
pubmed:issnType
Print
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
145-52
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
[Treatment of the unstable bladder in children with the anticholinergic agent propiverin hydrochloride (mictonorm/mictonets)].
pubmed:publicationType
Journal Article, English Abstract