Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1985-7-25
pubmed:abstractText
The metabolism of all-trans-[15-14C]retinoic acid in vitamin A-adequate or vitamin A-deficient rats fed retinoic acid was studied following intratesticular injection. Analysis of testicular metabolites by HPLC at 1, 6, and 24 h demonstrated that the retinoic acid was isomerized to 13-cis-retinoic acid and metabolized to polar metabolites in both groups of rats at all time periods. However, polar metabolites predominated in the testes of the vitamin A-deficient rats. At 24 h the total radioactivity remaining in the testis was much lower in the testes of vitamin A-deficient rats than in normal animals suggesting a faster rate of metabolism of all-trans-retinoic acid in these rats.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-9831
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
17-23
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Metabolism of all-trans-retinoic acid in rat testis.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.