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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1985-7-18
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pubmed:abstractText |
In a 61-year-old woman, who had been exposed for 20 years to cadmium in the production of Ni-Cd batteries, nephrectomy of the contracted kidney was performed. The removed kidney was examined histologically and the cadmium concentration was determined in the cortex (44.97 micrograms g-1) and in the medulla (7.71 micrograms g-1). The homogenates of the renal cortex and medulla were subjected to gel filtration on Sephadex G-75. In the cortex, as well as the medulla, cadmium was predominantly found in the low-molecular (metallothionein) fraction, but in the cortex, Cd content in this fraction was six times higher than in the medulla. The determination of SH groups and proteins in high- and low-molecular fractions indicates an induction of the metallothionein formation primarily in the renal cortex.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0340-0131
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
241-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3997265-Cadmium,
pubmed-meshheading:3997265-Environmental Exposure,
pubmed-meshheading:3997265-Female,
pubmed-meshheading:3997265-Glutathione,
pubmed-meshheading:3997265-Humans,
pubmed-meshheading:3997265-Kidney,
pubmed-meshheading:3997265-Middle Aged,
pubmed-meshheading:3997265-Nephrectomy
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pubmed:year |
1985
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pubmed:articleTitle |
Analysis of the renal tissue of a woman chronically exposed to cadmium.
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pubmed:publicationType |
Journal Article
|