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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1985-6-20
|
| pubmed:abstractText |
Ketoconazole, administered as a single oral dose depressed ovarian concentration of estradiol-17 beta in rats. Estradiol-17 beta was quantitated, following dansylation, by a high-performance-liquid-chromatographic method. Control proestrous concentration was 111.2 +/- 6.9 pg/mg. With ketoconazole doses of 5 mg/kg and 20 mg/kg, the estrogen concentration was reduced to 84.0 +/- 8.4 pg/mg and 34.6 +/- 5.0 pg/mg respectively.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0034-5164
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
48
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
141-4
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:3992027-Administration, Oral,
pubmed-meshheading:3992027-Animals,
pubmed-meshheading:3992027-Estradiol,
pubmed-meshheading:3992027-Female,
pubmed-meshheading:3992027-Ketoconazole,
pubmed-meshheading:3992027-Ovary,
pubmed-meshheading:3992027-Rats,
pubmed-meshheading:3992027-Rats, Inbred Strains
|
| pubmed:year |
1985
|
| pubmed:articleTitle |
Depression of ovarian estradiol-17 beta following single oral dose of ketoconazole.
|
| pubmed:publicationType |
Journal Article
|