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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1985-4-12
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pubmed:abstractText |
Intracellular calmodulin levels were measured by direct radioimmunoassay in spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY). Decreased calmodulin levels were demonstrated in the brain, heart, aorta and kidney of spontaneously hypertensive rats compared with those in Wistar-Kyoto rats. Calmodulin levels in the brain were also decreased in deoxycorticosterone acetate (DOCA)-salt rats, but not changed significantly in the heart, aorta and kidney compared with those in Wistar-Kyoto rats. These findings suggest that intracellular calcium-dependent regulatory systems are genetically disrupted in spontaneously hypertensive rats, but this is probably not an important factor in the development of hypertension.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0143-5221
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
407-10
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3971670-Animals,
pubmed-meshheading:3971670-Aorta,
pubmed-meshheading:3971670-Brain Chemistry,
pubmed-meshheading:3971670-Calmodulin,
pubmed-meshheading:3971670-Desoxycorticosterone,
pubmed-meshheading:3971670-Hypertension,
pubmed-meshheading:3971670-Kidney,
pubmed-meshheading:3971670-Male,
pubmed-meshheading:3971670-Myocardium,
pubmed-meshheading:3971670-Radioimmunoassay,
pubmed-meshheading:3971670-Rats,
pubmed-meshheading:3971670-Rats, Inbred SHR,
pubmed-meshheading:3971670-Rats, Inbred WKY
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pubmed:year |
1985
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pubmed:articleTitle |
Calmodulin levels in hypertensive rats.
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pubmed:publicationType |
Journal Article,
Comparative Study
|