Linked Life Data

3970454

Source:http://linkedlifedata.com/resource/pubmed/id/3970454

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1985-3-20
pubmed:abstractText
The purpose of this study was to evaluate whether the previously demonstrated improvement in contractile tension of diaphragmatic muscle with aminophylline results in improved ventilatory endurance. We measured the maximal sustained ventilatory levels during prolonged isocapnic hyperpnea as an index of ventilatory muscle function. This measurement was made in 7 normal subjects and 7 patients with chronic obstructive pulmonary disease during the intravenous administration of saline and aminophylline on 2 separate days. The order of administration of the infusions was randomized. Although both groups showed slightly higher sustained ventilatory levels during aminophylline infusion, the magnitude of change was small and unlikely to have a significant clinical benefit in the setting of respiratory muscle fatigue.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0003-0805
pubmed:author
pubmed:issnType
Print
pubmed:volume
131
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
226-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Aminophylline and its influence on ventilatory endurance in humans.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Research Support, U.S. Gov't, P.H.S., Randomized Controlled Trial, Research Support, Non-U.S. Gov't