Linked Life Data

3953250

Source:http://linkedlifedata.com/resource/pubmed/id/3953250

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-4-14
pubmed:abstractText
The dysontogenesis of the brain ventricle system of golden hamster fetuses was studied after X-ray irradiation of the mother at different stages of pregnancy. Groups of gravid hamsters were irradiated with a single dose (200 R) on either the 6th, 8th, 10th or 12th day of gestation. The fetuses were removed 1 day before birth. The most prominent finding in all stages of development was the dilatation of the brain ventricles. In addition to hydrocephalus, hematocephaly was also found in some cases. Furthermore, a widening of the central canal of the spinal cord with hemorrhagic content could sometimes be observed. Ependymal ectopies and subependymal rosettes occurred more frequently when irradiation was given in the late fetal period. The experimental findings demonstrate that after irradiation of the mother animal, malformation of the brain may be produced during the whole intrauterine period of development. The pattern and extent of malformation depend not only upon the dose of irradiation but also upon the stage of development at which irradiation was given.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0001-5180
pubmed:author
pubmed:issnType
Print
pubmed:volume
125
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
121-5
pubmed:dateRevised
2007-7-2
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Radiation-induced developmental abnormalities of the brain ventricles in the golden hamster.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't