Linked Life Data

3939495

Source:http://linkedlifedata.com/resource/pubmed/id/3939495

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1986-12-17
pubmed:abstractText
Mammary gland tumors induced by 7,12-dimethylbenz(a)-anthracene (DMBA) in female Wistar rats could be divided into secreting and nonsecreting ones. Histological, histochemical, cytophotometric, and electron microscopic examinations yielded indirect evidence for the ab ovo malignant nature of the nonsecreting tumors but not for the secreting ones. Nonsecreting tumors showed high total lactate dehydrogenase (LDH) activity and a definite shift of the isoenzyme pattern toward isoenzymes containing M subunits compared to those of lactating mammary glands. Secreting tumors could be characterized by low total LDH activity and a moderate increase of M/H ratio. These biochemical results support the hypothesis that nonsecreting mammary tumors induced in rats--independently of metastatization and differentiation--have to be considered carcinomas while the secreting ones benign adenomas.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0730-8485
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
41-6
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Relationship between histological structure and lactate dehydrogenase isoenzyme pattern of rat mammary tumors induced by dimethylbenz(a)-anthracene.
pubmed:publicationType
Journal Article