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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1985-11-21
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pubmed:abstractText |
Male Fischer F-344 rats were given ethanol in the drinking water and/or by single oral administration. Following this, the animals received p.o. 100 ng/kg of the hepatocarcinogen [3H]aflatoxin B1 (AFB1). 24 h later, the level of DNA-bound AFB1 was determined in the liver and was found not to be affected by any type of ethanol pretreatment. A cocarcinogenic effect of ethanol in the liver is therefore unlikely to be due to an effect on the metabolic activation inactivation processes governing the formation of DNA-binding AFB1 metabolites.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
|
pubmed:issn |
0014-4754
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
41
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1338-40
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3930282-Administration, Oral,
pubmed-meshheading:3930282-Aflatoxin B1,
pubmed-meshheading:3930282-Aflatoxins,
pubmed-meshheading:3930282-Animals,
pubmed-meshheading:3930282-Cocarcinogenesis,
pubmed-meshheading:3930282-DNA,
pubmed-meshheading:3930282-Ethanol,
pubmed-meshheading:3930282-Liver,
pubmed-meshheading:3930282-Liver Neoplasms,
pubmed-meshheading:3930282-Rats,
pubmed-meshheading:3930282-Rats, Inbred F344
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pubmed:year |
1985
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pubmed:articleTitle |
Covalent binding of aflatoxin B1 to liver DNA in rats pretreated with ethanol.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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