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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1985-8-22
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pubmed:abstractText |
Chronic quartan malarial infection has been established in the common marmoset (Callithrix jacchus). Plasmodium brasilianum from a douroucouli monkey (Aotus trivirgatus) was used to infect splenectomized twin animals, passed to an intact animal, and then to 4 other intact adults, 2 pairs of twins. In 2 of the 4 latter animals there was continuing patency with parasitaemias of less than or equal to 0.5% parasitized erythrocytes for 30 weeks. The other 2 had lower initial levels of parasitaemia; in 1 of these parasitaemias remained low or subpatent. All marmosets developed lymphocytosis. One animal became ill 30 weeks after infection with anaemia, weight loss and mild proteinurea, the other 3 remained well. Histological examination showed minor changes in the kidneys; spleens of infected animals showed marked follicular hyperplasia and phagocytosis of pigment. The livers showed sinusoidal hypercellularity and pigment deposition and in splenectomized animals, a marked lymphoid follicular hyperplasia in the portal tracts.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0031-1820
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
90 ( Pt 3)
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
573-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3925423-Animals,
pubmed-meshheading:3925423-Aotus trivirgatus,
pubmed-meshheading:3925423-Callithrix,
pubmed-meshheading:3925423-Callitrichinae,
pubmed-meshheading:3925423-Disease Models, Animal,
pubmed-meshheading:3925423-Female,
pubmed-meshheading:3925423-Host-Parasite Interactions,
pubmed-meshheading:3925423-Hyperplasia,
pubmed-meshheading:3925423-Liver Diseases, Parasitic,
pubmed-meshheading:3925423-Lymphocytosis,
pubmed-meshheading:3925423-Malaria,
pubmed-meshheading:3925423-Male,
pubmed-meshheading:3925423-Phagocytosis,
pubmed-meshheading:3925423-Plasmodium,
pubmed-meshheading:3925423-Spleen,
pubmed-meshheading:3925423-Splenectomy
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pubmed:year |
1985
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pubmed:articleTitle |
Plasmodium brasilianum in the common marmoset Callithrix jacchus.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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