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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1985-2-4
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pubmed:abstractText |
The effects of intravenous nitroglycerin (NTG) upon the bleeding time, platelet aggregation response, and plasma 6-keto-PGF1 alpha concentration were measured in 17 patients about to undergo coronary bypass grafting. NTG produced a dose-related prolongation of the bleeding time that correlated with the accompanying decrease in systolic blood pressure. Platelet aggregation was not affected and measurements of 6-keto-PGF1 alpha failed to reveal detectable levels (less than 10 pg/ml) either before or after NTG infusion. This suggests that the prolonged bleeding time associated with NTG infusion may be due to vasodilation and increased venous capacitance, rather than altered vascular-platelet interaction.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
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pubmed:issn |
0003-2999
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
30-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3917623-Adult,
pubmed-meshheading:3917623-Aged,
pubmed-meshheading:3917623-Bleeding Time,
pubmed-meshheading:3917623-Dose-Response Relationship, Drug,
pubmed-meshheading:3917623-Epoprostenol,
pubmed-meshheading:3917623-Female,
pubmed-meshheading:3917623-Humans,
pubmed-meshheading:3917623-Infusions, Parenteral,
pubmed-meshheading:3917623-Male,
pubmed-meshheading:3917623-Middle Aged,
pubmed-meshheading:3917623-Nitroglycerin,
pubmed-meshheading:3917623-Platelet Aggregation,
pubmed-meshheading:3917623-Platelet Function Tests
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pubmed:year |
1985
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pubmed:articleTitle |
Dose-related prolongation of the bleeding time by intravenous nitroglycerin.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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