Linked Life Data

391545

Source:http://linkedlifedata.com/resource/pubmed/id/391545

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1980-3-17
pubmed:abstractText
The authors make a review and critical evaluation of the accumulated experimental material for clarifying the question: whether drinking is physiological process due to exogenously administered angiotensin II (A-II) or to endogenous stimulation of the rena renin-angiotensin system (RAS). There is a parallel between water intake and plasma renin activity (PRA) in states like hypovolemia, hemorrhagia, hypotension, sodium loss, etc. They find sensitivity of some cerebral structures without blood-brain barrier to physiological concentations of A-II. Water intake is increased after venous administration of angiotensin-II within physiological concentrations. It is shown at the same time that central blockade of A-II does not inhibit drinking after water abstention. The authors discover that some effects, leading to an increased water intake, are not due to RAS. Nephrectomy does not alter circadian thythm of drinking of water. They discuss contradiction in experimental data and make an inference that renal RAS could not be considered as a single and sufficient factor for regulation of water intake.
pubmed:language
bul
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0367-0643
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
193-200
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
[Kidney renin-angiotensin system and water intake].
pubmed:publicationType
Journal Article, English Abstract, Review