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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1986-7-25
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pubmed:abstractText |
Chronic diuretic therapy in hypertensive patients may be associated with a reversible deterioration in glucose tolerance. There is evidence to suggest that beta-blocker monotherapy may cause a deterioration in glucose tolerance in patients with non-insulin-dependent diabetes mellitus but little information about the effects of chronic beta-blocker treatment in hypertensive patients with normal glucose metabolism. A prospective evaluation of the effects of propranolol monotherapy on glucose tolerance was performed in 13 nondiabetic hypertensive patients. One patient developed diabetes mellitus after 1 month of treatment. Of 11 patients, 4 had a 30% or greater increase in fasting glucose after 1 year of therapy and a significant increase in fasting, and 2-hour postglucose-load venous plasma glucose occurred in the 9 patients completing 18 months of treatment. Although the biologic significance of these changes is questionable, the development of hyperglycemia in a patient receiving beta blockers could represent a side effect of drug therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0748-450X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
138-44
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:3915320-Adult,
pubmed-meshheading:3915320-Aged,
pubmed-meshheading:3915320-Blood Glucose,
pubmed-meshheading:3915320-Female,
pubmed-meshheading:3915320-Glucose Tolerance Test,
pubmed-meshheading:3915320-Humans,
pubmed-meshheading:3915320-Hypertension,
pubmed-meshheading:3915320-Insulin,
pubmed-meshheading:3915320-Male,
pubmed-meshheading:3915320-Middle Aged,
pubmed-meshheading:3915320-Propranolol,
pubmed-meshheading:3915320-Prospective Studies,
pubmed-meshheading:3915320-Time Factors
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pubmed:year |
1985
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pubmed:articleTitle |
Glucose tolerance during chronic propranolol treatment.
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pubmed:publicationType |
Journal Article
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