Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1986-3-12
pubmed:abstractText
Current knowledge of primary culturing and establishment of continuous cell lines from human plasmacytomas are reviewed. The cells derived from chronic monoclonal tumors are capable of proliferating in culture no more than for 3 weeks. The enrichment of the media with nutrient supplements and growth factors does not improve the cell survival. Most of the described stable cell lines were derived from malignancies of the late stages of tumor progression. Cell lines producing complete molecules of immunoglobulins were established with the aid of sophisticated culturing methods. The microenvironment and growth factors in culture system favoured the survival of transformed plasma cells which retained a high level of differentiation.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0041-3771
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1215-27
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
[Cultivation of human plasmacytoma cells].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract, Review