Linked Life Data

3908221

Source:http://linkedlifedata.com/resource/pubmed/id/3908221

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1986-2-19
pubmed:abstractText
Transcription of the tightly linked genes GAL7-GAL10-GAL1 encoding three galactose-metabolizing enzymes in Saccharomyces cerevisiae is regulated by an interplay of the positive regulatory gene GAL4 and the negative regulatory gene GAL80. The concentration of GAL80 mRNA (determined by a quantitative blot hybridization) was nearly comparable to that of URA3 mRNA, in the wild-type yeast grown in medium with glucose or glycerol. The intracellular concentration of GAL80 mRNA increased by changing the carbon source to galactose by a factor of more than 5, in contrast to a GAL4 mRNA concentration which is essentially unaffected by galactose [Laughon and Gesteland, Proc. Natl. Acad. Sci. USA 79 (1982) 6827-6831]. The inducible expression of the GAL80 gene was suggested to involve its own product and also the product of GAL4 by using various mutations in those genes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0378-1119
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Controlled transcription of the yeast regulatory gene GAL80.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't