Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1985-12-24
pubmed:abstractText
Fibronectin is a large multifunctional glycoprotein present both in soluble form in plasma and other body fluids and in an insoluble form in interstitial connective tissues and in association with most basement membranes. The protein seems to provide a link between circulating body fluids, cell surfaces and the extracellular matrix. At sites of injury, fibronectin, covalently cross-linked to the fibrin clot, may provide a growth substratum for the invading cells and appears through its multiple interactions with other matrix components and cell surfaces to be involved in the organization of the matrix that will replace the clot. Fibronectin deposition may serve as a useful early marker for connective tissue formation in pathological processes and its fragmentation may serve as an indicator of pathological conditions involving proteolytic events.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-5208
pubmed:author
pubmed:issnType
Print
pubmed:volume
114
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
111-26
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Fibronectin in formation and degradation of the pericellular matrix.
pubmed:publicationType
Journal Article