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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1985-12-12
|
| pubmed:abstractText |
The title compounds were synthesized and tested for mutagenicity on Salmonella typhimurium TA98 in the presence of S9 mix. All test compounds showed lower activity than their respective 3-methyl analogues (IQ compounds). The replacement of the 3-methyl by an ethyl group should not alter the chemistry of these compounds; hence, their lower mutagenic activity could merely be of steric origin.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0027-5107
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
144
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
131-6
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3903482-Imidazoles,
pubmed-meshheading:3903482-Mutagenicity Tests,
pubmed-meshheading:3903482-Mutagens,
pubmed-meshheading:3903482-Quinolines,
pubmed-meshheading:3903482-Quinoxalines,
pubmed-meshheading:3903482-Salmonella typhimurium,
pubmed-meshheading:3903482-Structure-Activity Relationship
|
| pubmed:year |
1985
|
| pubmed:articleTitle |
The synthesis and mutagenicity of the 3-ethyl analogues of the potent mutagens IQ, MeIQ, MeIQx and its 3,7-dimethyl isomer.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|