pubmed-article:3896173 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3896173 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:3896173 | lifeskim:mentions | umls-concept:C0543467 | lld:lifeskim |
pubmed-article:3896173 | lifeskim:mentions | umls-concept:C0007202 | lld:lifeskim |
pubmed-article:3896173 | lifeskim:mentions | umls-concept:C0542341 | lld:lifeskim |
pubmed-article:3896173 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:3896173 | lifeskim:mentions | umls-concept:C0173022 | lld:lifeskim |
pubmed-article:3896173 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:3896173 | pubmed:dateCreated | 1985-9-12 | lld:pubmed |
pubmed-article:3896173 | pubmed:abstractText | We measured the rate of clearance of technetium 99m-labeled diethylenetriamine pentaacetate (99mTcDTPA) (molecular weight, 492 daltons) from the lung into the blood (T1/2LB) in 9 patients before and after operation with cardiopulmonary bypass (CPB). Two hours postoperatively, T1/2LB fell from 49.3 +/- 13.6 minutes (mean +/- standard deviation) to 24.0 +/- 12.8 minutes (p less than 0.001). In addition, alveolar-arterial oxygen tension difference P(A-a)O2 had increased from 73 +/- 28 mm Hg to 164 +/- 37 mm Hg (p less than 0.001). The rates of clearance of 99mTcDTPA had returned to preoperative times by 7 days after operation, although there was still a significant (p less than 0.05) elevation in P(A-a)O2. Postoperative respiratory failure developed in 1 patient. The only abnormality of lung function detected preoperatively was an increased clearance rate for 99mTcDTPA (T1/2LB, 18 minutes). This study has shown an increased clearance from the lung of a low-molecular-weight molecule following operation with CPB. This finding should allow a more rational approach to elucidating the mechanisms of injury to the gas-blood interface in the lung following this type of operation. | lld:pubmed |
pubmed-article:3896173 | pubmed:language | eng | lld:pubmed |
pubmed-article:3896173 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3896173 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:3896173 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3896173 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3896173 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3896173 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3896173 | pubmed:month | Aug | lld:pubmed |
pubmed-article:3896173 | pubmed:issn | 0003-4975 | lld:pubmed |
pubmed-article:3896173 | pubmed:author | pubmed-author:MintyB DBD | lld:pubmed |
pubmed-article:3896173 | pubmed:author | pubmed-author:RoystonDD | lld:pubmed |
pubmed-article:3896173 | pubmed:author | pubmed-author:WallworkJJ | lld:pubmed |
pubmed-article:3896173 | pubmed:author | pubmed-author:JonesG JGJ | lld:pubmed |
pubmed-article:3896173 | pubmed:author | pubmed-author:HigenbottamT... | lld:pubmed |
pubmed-article:3896173 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3896173 | pubmed:volume | 40 | lld:pubmed |
pubmed-article:3896173 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3896173 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3896173 | pubmed:pagination | 139-43 | lld:pubmed |
pubmed-article:3896173 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:3896173 | pubmed:year | 1985 | lld:pubmed |
pubmed-article:3896173 | pubmed:articleTitle | The effect of surgery with cardiopulmonary bypass on alveolar-capillary barrier function in human beings. | lld:pubmed |
pubmed-article:3896173 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3896173 | pubmed:publicationType | Comparative Study | lld:pubmed |
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