Linked Life Data

3879221

Source:http://linkedlifedata.com/resource/pubmed/id/3879221

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1986-4-3
pubmed:abstractText
[3H]MPP+ (1-[methyl-3H]4-phenylpyridinium) is taken up into rat striatal slices in a temperature-, time- and Na+-dependent process blocked by dopamine (DA) uptake inhibitors. Once taken up, authentic [3H]MPP+ is released at 37 degrees C by 15 mM KCl. This release is inhibited by (-)N-propyl-norapomorphine and enhanced by (-)sulpiride, as observed under the same conditions for [3H]DA release. Thus, rat striatal DA-ergic nerve endings do not discriminate between DA and MPP+ for their active transport and DA autoreceptor-regulated release.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0014-2999
pubmed:author
pubmed:issnType
Print
pubmed:day
17
pubmed:volume
119
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
247-50
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Evidence for the release of 1-methyl-4-phenylpyridinium (MPP+) from rat striatal neurons in vitro.
pubmed:publicationType
Journal Article, In Vitro